InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: HADHA

Summary

InnateDB Protein

IDBP-689112.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HADHA

Protein Name

trifunctional enzyme subunit alpha, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000020020

InnateDB Gene

IDBG-637102 (HADHA)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 51 interaction(s) predicted by orthology.

Predicted by orthology
Total	51 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
GO:0004300	enoyl-CoA hydratase activity
GO:0005515	protein binding
GO:0016491	oxidoreductase activity
GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050662	coenzyme binding

Biological Process

GO:0006631	fatty acid metabolic process
GO:0006635	fatty acid beta-oxidation
GO:0008152	metabolic process
GO:0032868	response to insulin
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016507	mitochondrial fatty acid beta-oxidation multienzyme complex
GO:0042645	mitochondrial nucleoid

Protein Structure and Domains

PDB ID

InterPro

IPR001753 Crotonase superfamily
IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal
IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding
IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR012803 Fatty acid oxidation complex, alpha subunit, mitochondrial
IPR029045 ClpP/crotonase-like domain

PFAM

PF00378
PF00725
PF02737

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-