InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.103632

Summary

InnateDB Protein

IDBP-689274.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.103632

Protein Name

low-density lipoprotein receptor-related protein 4

Synonyms

MEGF7;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000041521

InnateDB Gene

IDBG-637271 (BT.103632)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0030971	receptor tyrosine kinase binding
GO:0042803	protein homodimerization activity

Biological Process

GO:0001822	kidney development
GO:0001932	regulation of protein phosphorylation
GO:0001942	hair follicle development
GO:0008104	protein localization
GO:0009953	dorsal/ventral pattern formation
GO:0009954	proximal/distal pattern formation
GO:0030178	negative regulation of Wnt signaling pathway
GO:0030279	negative regulation of ossification
GO:0030326	embryonic limb morphogenesis
GO:0042475	odontogenesis of dentin-containing tooth
GO:0042733	embryonic digit morphogenesis
GO:0043113	receptor clustering
GO:0048856	anatomical structure development
GO:0050771	negative regulation of axonogenesis
GO:0051124	synaptic growth at neuromuscular junction
GO:0060173	limb development
GO:0071340	skeletal muscle acetylcholine-gated channel clustering
GO:0090090	negative regulation of canonical Wnt signaling pathway
GO:0097104	postsynaptic membrane assembly
GO:0097105	presynaptic membrane assembly
GO:1901631	positive regulation of presynaptic membrane organization

Cellular Component

GO:0005886	plasma membrane
GO:0031594	neuromuscular junction

Protein Structure and Domains

PDB ID

InterPro

IPR000033 LDLR class B repeat
IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR009030 Insulin-like growth factor binding protein, N-terminal
IPR013658 SMP-30/Gluconolactonase/LRE-like region

PFAM

PF00058
PF00008
PF07645
PF00057
PF08450

PRINTS

PR00261

PIRSF

SMART

SM00135
SM00181
SM00179
SM00192

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt