Version 5.4
Bos taurus Gene: BT.103632
Summary
InnateDB Gene IDBG-637271.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.103632
Gene Name low-density lipoprotein receptor-related protein 4 precursor
Synonyms MEGF7
Species Bos taurus
Ensembl Gene ENSBTAG00000008429
Encoded Proteins
IDBP-689274
low-density lipoprotein receptor-related protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000134569:
This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:77663792-77701236
Strand Reverse strand
Band
Transcripts
ENSBTAT00000043997 ENSBTAP00000041521
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0030971 receptor tyrosine kinase binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0001822 kidney development
GO:0001932 regulation of protein phosphorylation
GO:0001942 hair follicle development
GO:0008104 protein localization
GO:0009953 dorsal/ventral pattern formation
GO:0009954 proximal/distal pattern formation
GO:0030178 negative regulation of Wnt signaling pathway
GO:0030279 negative regulation of ossification
GO:0030326 embryonic limb morphogenesis
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042733 embryonic digit morphogenesis
GO:0043113 receptor clustering
GO:0048856 anatomical structure development
GO:0050771 negative regulation of axonogenesis
GO:0051124 synaptic growth at neuromuscular junction
GO:0060173 limb development
GO:0071340 skeletal muscle acetylcholine-gated channel clustering
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0097104 postsynaptic membrane assembly
GO:0097105 presynaptic membrane assembly
GO:1901631 positive regulation of presynaptic membrane organization
Cellular Component
GO:0005886 plasma membrane
GO:0031594 neuromuscular junction
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000134569
View Gene Order
ENSMUSG00000027253
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_118779
Extracellular matrix organization pathway
REACT_163906
ECM proteoglycans pathway
REACT_206066
Extracellular matrix organization pathway
REACT_196606
ECM proteoglycans pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1ML31
UniProt Splice Variant
Entrez Gene 504317
UniGene Bt.103632
RefSeq NM_001077843
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02041587
GenPept
RNA Seq Atlas 504317

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca