InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: MADD

Summary

InnateDB Protein

IDBP-689370.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MADD

Protein Name

MAP-kinase activating death domain

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000028927

InnateDB Gene

IDBG-637361 (MADD)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0017112	Rab guanyl-nucleotide exchange factor activity

Biological Process

GO:0000187	activation of MAPK activity
GO:0032483	regulation of Rab protein signal transduction
GO:0032851	positive regulation of Rab GTPase activity
GO:0042981	regulation of apoptotic process
GO:0051726	regulation of cell cycle
GO:0097194	execution phase of apoptosis
GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001234	negative regulation of apoptotic signaling pathway
GO:2001236	regulation of extrinsic apoptotic signaling pathway