Bos taurus Protein: ITSN2
Summary
InnateDB Protein IDBP-689465.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ITSN2
Protein Name intersectin 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000029334
InnateDB Gene IDBG-637359 (ITSN2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 81 interaction(s) predicted by orthology.
Predicted by orthology
Total 81 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0006897 endocytosis
GO:0032321 positive regulation of Rho GTPase activity
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
IPR000219 Dbl homology (DH) domain
IPR000261 EPS15 homology (EH)
IPR001452 SH3 domain
IPR001849 Pleckstrin homology domain
IPR002048 EF-hand domain
IPR011511 Variant SH3 domain
PFAM PF00168
PF00621
PF00018
PF14604
PF00169
PF00036
PF13202
PF13405
PF07653
PRINTS PR00360
PR00452
PIRSF
SMART SM00239
SM00325
SM00027
SM00326
SM00233
SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MC50
UniProt Splice Variant
Entrez Gene 521706
UniGene Bt.109622
RefSeq XP_002691512
HUGO HGNC:6184
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02031675 DAAA02031676 DAAA02031677
GenPept