Version 5.4
| Bos taurus Gene: ITSN2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-637359.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | ITSN2 | ||||||||
| Gene Name | Uncharacterized protein | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000023172 | ||||||||
| Encoded Proteins |
intersectin 2
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198399:
This gene encodes a cytoplasmic protein which contains SH3 domains. This protein is a member of a family of proteins involved in clathrin-mediated endocytosis. Intersectin 2 is thought to regulate the formation of clathrin-coated vesicles and also may function in the induction of T cell antigen receptor (TCR) endocytosis. Alternatively spliced transcript variants have been found for this gene that encode three distinct isoforms. Additional variants have been found but their full length nature has not been determined. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 11:74895799-74982112 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 81 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
EGFR1 pathway
TCR pathway
TSLP pathway
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| REACTOME | |||||||||
| KEGG | |||||||||
| INOH | |||||||||
| PID NCI |
Regulation of CDC42 activity
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | F1MC50 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 521706 | ||||||||
| UniGene | Bt.109622 | ||||||||
| RefSeq | |||||||||
| HUGO | HGNC:6184 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02031675 DAAA02031676 DAAA02031677 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 101903424 521706 | ||||||||