InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DHX36

Summary

InnateDB Protein

IDBP-689499.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DHX36

Protein Name

probable ATP-dependent RNA helicase DHX36

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000008082

InnateDB Gene

IDBG-637479 (DHX36)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.

Predicted by orthology
Total	26 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0001047	core promoter binding
GO:0002151	G-quadruplex RNA binding
GO:0003676	nucleic acid binding
GO:0003725	double-stranded RNA binding
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0008094	DNA-dependent ATPase activity
GO:0016787	hydrolase activity
GO:0042826	histone deacetylase binding
GO:0044212	transcription regulatory region DNA binding
GO:0044822	poly(A) RNA binding
GO:0051880	G-quadruplex DNA binding

Biological Process

GO:0001503	ossification
GO:0006200	ATP catabolic process
GO:0008152	metabolic process
GO:0009615	response to virus
GO:0010501	RNA secondary structure unwinding
GO:0032206	positive regulation of telomere maintenance
GO:0043330	response to exogenous dsRNA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR001650 Helicase, C-terminal
IPR007502 Helicase-associated domain
IPR011545 DEAD/DEAH box helicase domain
IPR011709 Domain of unknown function DUF1605
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF04408
PF00270
PF07717

PRINTS

PIRSF

SMART

SM00490
SM00847
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite