InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: P2RY12

Summary

InnateDB Protein

IDBP-689631.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

P2RY12

Protein Name

P2Y purinoceptor 12

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000041984

InnateDB Gene

IDBG-637609 (P2RY12)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001609	G-protein coupled adenosine receptor activity
GO:0001621	ADP receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0045028	G-protein coupled purinergic nucleotide receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007596	blood coagulation
GO:0030168	platelet activation
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
GO:0043270	positive regulation of ion transport
GO:0070527	platelet aggregation

Cellular Component

GO:0016021	integral component of membrane
GO:0031224	intrinsic component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR002282 Platelet-activating factor receptor
IPR005394 P2Y12 purinoceptor
IPR005466 P2Y14 purinoceptor
IPR008109 P2Y13 purinoceptor
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00237
PR01153
PR01569
PR01655
PR01735

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite