InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: P2RY12

Summary

InnateDB Gene

IDBG-637609.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

P2RY12

Gene Name

P2Y purinoceptor 12

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000015837

Encoded Proteins

IDBP-689631

P2Y purinoceptor 12

IDBP-689636

P2Y purinoceptor 12

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169313:
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:117588523-117640789

Strand

Forward strand

Band

Transcripts

ENSBTAT00000044491	ENSBTAP00000041984
ENSBTAT00000064076	ENSBTAP00000055434

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001609	G-protein coupled adenosine receptor activity
GO:0001621	ADP receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0045028	G-protein coupled purinergic nucleotide receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007596	blood coagulation
GO:0030168	platelet activation
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway
GO:0043270	positive regulation of ion transport
GO:0070527	platelet aggregation