InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PTPN14

Summary

InnateDB Protein

IDBP-689857.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTPN14

Protein Name

protein tyrosine phosphatase, non-receptor type 14

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000028717

InnateDB Gene

IDBG-637822 (PTPN14)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003712	transcription cofactor activity
GO:0004721	phosphoprotein phosphatase activity
GO:0004725	protein tyrosine phosphatase activity
GO:0005515	protein binding
GO:0016787	hydrolase activity
GO:0016791	phosphatase activity
GO:0030971	receptor tyrosine kinase binding

Biological Process

GO:0001946	lymphangiogenesis
GO:0006470	protein dephosphorylation
GO:0008285	negative regulation of cell proliferation
GO:0016311	dephosphorylation
GO:0046825	regulation of protein export from nucleus

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005856	cytoskeleton

Protein Structure and Domains

PDB ID

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000299 FERM domain
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR003595 Protein-tyrosine phosphatase, catalytic
IPR014392 Protein-tyrosine phosphatase, non-receptor type-14, -21
IPR018979 FERM, N-terminal
IPR018980 FERM, C-terminal PH-like domain
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR019750 Band 4.1 family
IPR029021 Protein-tyrosine phosphatase-like
IPR029071 Ubiquitin-related domain

PFAM

PF00102
PF09379
PF09380
PF00373

PRINTS

PR00700
PR00935

PIRSF

PIRSF000934

SMART

SM00194
SM00404
SM00295

TIGRFAMs

Post-translational Modifications

Modification

Cross-References