InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: LPAR1

Summary

InnateDB Protein

IDBP-689868.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LPAR1

Protein Name

lysophosphatidic acid receptor 1

Synonyms

EDG2;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000012721

InnateDB Gene

IDBG-637833 (LPAR1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0030165	PDZ domain binding
GO:0070915	lysophosphatidic acid receptor activity

Biological Process

GO:0000187	activation of MAPK activity
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0032060	bleb assembly
GO:0035025	positive regulation of Rho protein signal transduction
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043410	positive regulation of MAPK cascade

Cellular Component

GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0030139	endocytic vesicle

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR002277 Lysophosphatidic acid receptor EDG-2
IPR004065 Lysophosphatidic acid receptor
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00237
PR01148
PR01527

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite