InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: OPTN

Summary

InnateDB Protein

IDBP-689966.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

OPTN

Protein Name

optineurin

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000021808

InnateDB Gene

IDBG-637914 (OPTN)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 71 interaction(s) predicted by orthology.

Predicted by orthology
Total	71 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0031593	polyubiquitin binding

Biological Process

GO:0000042	protein targeting to Golgi
GO:0001920	negative regulation of receptor recycling
GO:0007030	Golgi organization
GO:0016236	macroautophagy
GO:0034613	cellular protein localization
GO:0043001	Golgi to plasma membrane protein transport
GO:0050829	defense response to Gram-negative bacterium
GO:0090161	Golgi ribbon formation

Cellular Component

GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005802	trans-Golgi network
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR021063 NF-kappa-B essential modulator NEMO, N-terminal

PFAM

PF11577

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q3ZC32

UniProt Splice Variant

Entrez Gene

534150

UniGene

Bt.49466

RefSeq

NP_001029774

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC102937 DAAA02035514

GenPept

AAI02938