InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: ODC1

Summary

InnateDB Protein

IDBP-690253.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ODC1

Protein Name

Ornithine decarboxylase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000005575

InnateDB Gene

IDBG-638199 (ODC1)

Protein Structure

UniProt Annotation

Function

Key enzyme of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004586	ornithine decarboxylase activity
GO:0016829	lyase activity
GO:0016831	carboxy-lyase activity
GO:0042803	protein homodimerization activity

Biological Process

GO:0001822	kidney development
GO:0006596	polyamine biosynthetic process
GO:0008284	positive regulation of cell proliferation
GO:0033387	putrescine biosynthetic process from ornithine
GO:0042176	regulation of protein catabolic process

Cellular Component

GO:0005829

cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR000183 Ornithine/DAP/Arg decarboxylase
IPR002433 Ornithine decarboxylase
IPR009006 Alanine racemase/group IV decarboxylase, C-terminal
IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal
IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal
IPR029066 PLP-binding barrel

PFAM

PF00278
PF02784

PRINTS

PR01179
PR01182

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P27117