InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: XRN1

Summary

InnateDB Protein

IDBP-690322.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

XRN1

Protein Name

5'-3' exoribonuclease 1

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000015318

InnateDB Gene

IDBG-638223 (XRN1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.

Predicted by orthology
Total	26 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004527	exonuclease activity
GO:0005515	protein binding
GO:0008409	5'-3' exonuclease activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000956	nuclear-transcribed mRNA catabolic process
GO:0016075	rRNA catabolic process
GO:0071028	nuclear mRNA surveillance
GO:0071044	histone mRNA catabolic process
GO:0090305	nucleic acid phosphodiester bond hydrolysis

Cellular Component

GO:0000932	cytoplasmic mRNA processing body
GO:0005622	intracellular
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR004859 Putative 5-3 exonuclease
IPR016494 5\'-3\' exoribonuclease 1
IPR029060 PIN domain-like

PFAM

PF03159

PRINTS

PIRSF

PIRSF006743

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E1BMZ8

UniProt Splice Variant

Entrez Gene

540834

UniGene

RefSeq

XP_005201950

HUGO

HGNC:30654

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02002875 DAAA02002876 DAAA02002877

GenPept