InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: IRF6

Summary

InnateDB Protein

IDBP-690427.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IRF6

Protein Name

Interferon regulatory factor 6

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000054388

InnateDB Gene

IDBG-638354 (IRF6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000975	regulatory region DNA binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0007050	cell cycle arrest
GO:0008285	negative regulation of cell proliferation
GO:0030216	keratinocyte differentiation
GO:0043588	skin development
GO:0043616	keratinocyte proliferation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0048468	cell development
GO:0060644	mammary gland epithelial cell differentiation

Cellular Component

GO:0005737	cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001346 Interferon regulatory factor DNA-binding domain
IPR008984 SMAD/FHA domain
IPR019471 Interferon regulatory factor-3

PFAM

PF00605
PF10401

PRINTS

PR00267

PIRSF

SMART

SM00348

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G3MXW7

UniProt Splice Variant

Entrez Gene

614253

UniGene

Bt.28192

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02043812

GenPept