Bos taurus Protein: MPP7
Summary
InnateDB Protein IDBP-690763.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MPP7
Protein Name MAGUK p55 subfamily member 7
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000036176
InnateDB Gene IDBG-638675 (MPP7)
Protein Structure
UniProt Annotation
Function Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact (By similarity). {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Cell junction, adherens junction {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019904 protein domain specific binding
GO:0032947 protein complex scaffold
GO:0046982 protein heterodimerization activity
Biological Process
GO:0070830 tight junction assembly
GO:0071896 protein localization to adherens junction
Cellular Component
GO:0005739 mitochondrion
GO:0005912 adherens junction
GO:0005923 tight junction
GO:0016020 membrane
GO:0030054 cell junction
GO:0097025 MPP7-DLG1-LIN7 complex
Protein Structure and Domains
PDB ID
InterPro IPR001452 SH3 domain
IPR001478 PDZ domain
IPR004172 L27
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR011511 Variant SH3 domain
IPR014775 L27, C-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00018
PF14604
PF00595
PF13180
PF00625
PF07653
PF02828
PRINTS PR00452
PIRSF
SMART SM00326
SM00228
SM00569
SM00072
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A6QQZ7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 512659
UniGene Bt.47758
RefSeq NP_001093817
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC150055
GenPept AAI50056