Version 5.4
Bos taurus Protein: CALCOCO2
Summary
InnateDB Protein IDBP-690991.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CALCOCO2
Protein Name Calcium-binding and coiled-coil domain-containing protein 2
Synonyms NDP52;
Species Bos taurus
Ensembl Protein ENSBTAP00000010432
InnateDB Gene IDBG-638886 (CALCOCO2)
Protein Structure
UniProt Annotation
Function May play a role in ruffle formation and actin cytoskeleton organization. Seems to negatively regulate constitutive secretion (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, perinuclear region {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 66 interaction(s) predicted by orthology.
Predicted by orthology
Total 66 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0034341 response to interferon-gamma
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005856 cytoskeleton
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR012852 Coiled-coil transcriptional coactivator-like
PFAM PF07888
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O18737
PhosphoSite PhosphoSite-
TrEMBL B1H0X0
UniProt Splice Variant
Entrez Gene 281942
UniGene Bt.96716
RefSeq NP_776825
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB008852 BC146237 BC151569
GenPept AAI46238 AAI51570 BAA23587

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca