Version 5.4
Bos taurus Protein: SH2B1
Summary
InnateDB Protein IDBP-691076.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SH2B1
Protein Name SH2B adaptor protein 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000025587
InnateDB Gene IDBG-638958 (SH2B1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0005515 protein binding
Biological Process
GO:0006928 cellular component movement
GO:0030032 lamellipodium assembly
GO:0035556 intracellular signal transduction
GO:0045840 positive regulation of mitosis
GO:2000278 regulation of DNA biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000980 SH2 domain
IPR001849 Pleckstrin homology domain
IPR015012 Phenylalanine zipper
PFAM PF00017
PF14633
PF00169
PF08916
PRINTS PR00401
PIRSF
SMART SM00252
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G8CY04
UniProt Splice Variant
Entrez Gene 506066
UniGene Bt.24389
RefSeq NP_001192458
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02057886 HQ418502
GenPept AEP14550

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca