InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: GLRA2

Summary

InnateDB Protein

IDBP-691085.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GLRA2

Protein Name

glycine receptor, alpha 2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000022869

InnateDB Gene

IDBG-638973 (GLRA2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005230	extracellular ligand-gated ion channel activity
GO:0016594	glycine binding
GO:0016934	extracellular-glycine-gated chloride channel activity
GO:0022824	transmitter-gated ion channel activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006821	chloride transport
GO:0007218	neuropeptide signaling pathway
GO:0034220	ion transmembrane transport
GO:1902476	chloride transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0045202	synapse
GO:0045211	postsynaptic membrane

Protein Structure and Domains

PDB ID

InterPro

IPR006028 Gamma-aminobutyric acid A receptor/Glycine receptor alpha
IPR006029 Neurotransmitter-gated ion-channel transmembrane domain
IPR006201 Neurotransmitter-gated ion-channel
IPR006202 Neurotransmitter-gated ion-channel ligand-binding
IPR008127 Glycine receptor alpha
IPR008129 Glycine receptor alpha2

PFAM

PF02932
PF02931

PRINTS

PR00253
PR00252
PR01673
PR01675

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite