InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: GLRA2

Summary

InnateDB Gene

IDBG-638973.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GLRA2

Gene Name

glycine receptor subunit alpha-2 precursor

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000017209

Encoded Proteins

IDBP-691085

glycine receptor, alpha 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101958:
The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:136034407-136242903

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000022869

ENSBTAP00000022869

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005230	extracellular ligand-gated ion channel activity
GO:0016594	glycine binding
GO:0016934	extracellular-glycine-gated chloride channel activity
GO:0022824	transmitter-gated ion channel activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006821	chloride transport
GO:0007218	neuropeptide signaling pathway
GO:0034220	ion transmembrane transport
GO:1902476	chloride transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0045202	synapse
GO:0045211	postsynaptic membrane