Version 5.4
Bos taurus Protein: STXBP1
Summary
InnateDB Protein IDBP-691099.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STXBP1
Protein Name Syntaxin-binding protein 1
Synonyms Unc18-1;
Species Bos taurus
Ensembl Protein ENSBTAP00000050665
InnateDB Gene IDBG-638972 (STXBP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019905 syntaxin binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0002576 platelet degranulation
GO:0006887 exocytosis
GO:0006904 vesicle docking involved in exocytosis
GO:0007269 neurotransmitter secretion
GO:0007274 neuromuscular synaptic transmission
GO:0007412 axon target recognition
GO:0016188 synaptic vesicle maturation
GO:0016192 vesicle-mediated transport
GO:0032229 negative regulation of synaptic transmission, GABAergic
GO:0043524 negative regulation of neuron apoptotic process
GO:0045956 positive regulation of calcium ion-dependent exocytosis
GO:0060292 long term synaptic depression
GO:0070527 platelet aggregation
Cellular Component
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0031091 platelet alpha granule
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001619 Sec1-like protein
PFAM PF00995
PRINTS
PIRSF PIRSF005715
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F6R0H3
UniProt Splice Variant
Entrez Gene 282378
UniGene Bt.72190
RefSeq XP_005213231
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02032154 DAAA02032155 DAAA02032156
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca