InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: STXBP1

Summary

InnateDB Gene

IDBG-638972.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STXBP1

Gene Name

Syntaxin-binding protein 1

Synonyms

Unc18-1

Species

Bos taurus

Ensembl Gene

ENSBTAG00000003525

Encoded Proteins

IDBP-691099

Syntaxin-binding protein 1

IDBP-691105

Syntaxin-binding protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136854:
This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:98325785-98395251

Strand

Forward strand

Band

Transcripts

ENSBTAT00000056141	ENSBTAP00000050665
ENSBTAT00000004589	ENSBTAP00000004589

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	20 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019905	syntaxin binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0002576	platelet degranulation
GO:0006810	transport
GO:0006887	exocytosis
GO:0006904	vesicle docking involved in exocytosis
GO:0007269	neurotransmitter secretion
GO:0007274	neuromuscular synaptic transmission
GO:0007412	axon target recognition
GO:0015031	protein transport
GO:0016188	synaptic vesicle maturation
GO:0016192	vesicle-mediated transport
GO:0032229	negative regulation of synaptic transmission, GABAergic
GO:0043524	negative regulation of neuron apoptotic process
GO:0045956	positive regulation of calcium ion-dependent exocytosis
GO:0060292	long term synaptic depression
GO:0070527	platelet aggregation

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0031091	platelet alpha granule
GO:0070062	extracellular vesicular exosome