Version 5.4
Bos taurus Protein: TOPBP1
Summary
InnateDB Protein IDBP-691110.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TOPBP1
Protein Name topoisomerase (DNA) II binding protein 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000000686
InnateDB Gene IDBG-638950 (TOPBP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.
Predicted by orthology
Total 38 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
Biological Process
GO:0006974 cellular response to DNA damage stimulus
GO:0010212 response to ionizing radiation
Cellular Component
GO:0000794 condensed nuclear chromosome
GO:0001673 male germ cell nucleus
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016605 PML body
Protein Structure and Domains
PDB ID
InterPro IPR001357 BRCT domain
IPR016126 Secretoglobin
PFAM PF00533
PF12738
PF01099
PRINTS
PIRSF
SMART SM00292
SM00096
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3X684
UniProt Splice Variant
Entrez Gene 540574
UniGene Bt.13731
RefSeq NP_001193695
HUGO HGNC:17008
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02003073 DAAA02003074
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca