InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: SP2

Summary

InnateDB Protein

IDBP-691121.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SP2

Protein Name

Transcription factor Sp2

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000018253

InnateDB Gene

IDBG-639003 (SP2)

Protein Structure

UniProt Annotation

Function

Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0042826	histone deacetylase binding
GO:0046872	metal ion binding

Biological Process

GO:0001701	in utero embryonic development
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0035264	multicellular organism growth
GO:0048144	fibroblast proliferation
GO:0048568	embryonic organ development
GO:0072358	cardiovascular system development

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like

PFAM

PF00096

PRINTS

PIRSF

SMART

SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q5E9U0

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

534403

UniGene

Bt.69289

RefSeq

NP_001015654

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC151610 BT020830

GenPept

AAI51611 AAX08847