Version 5.4
Bos taurus Gene: SP2
Summary
InnateDB Gene IDBG-639003.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SP2
Gene Name Transcription factor Sp2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013740
Encoded Proteins
IDBP-691121
Transcription factor Sp2
IDBP-691124
Transcription factor Sp2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167182:
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:39194570-39296546
Strand Reverse strand
Band
Transcripts
ENSBTAT00000018253 ENSBTAP00000018253
ENSBTAT00000064585 ENSBTAP00000054632
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0042826 histone deacetylase binding
GO:0046872 metal ion binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0035264 multicellular organism growth
GO:0048144 fibroblast proliferation
GO:0048568 embryonic organ development
GO:0072358 cardiovascular system development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000167182
View Gene Order
ENSMUSG00000018678
View Gene Order
Cross-References
SwissProt Q5E9U0
TrEMBL
UniProt Splice Variant
Entrez Gene 534403
UniGene Bt.25783 Bt.69289
RefSeq NM_001015654 XM_005220586 XM_005220587
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC151610 BT020830
GenPept AAI51611 AAX08847
RNA Seq Atlas 534403

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca