InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: NPHP3

Summary

InnateDB Protein

IDBP-691147.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NPHP3

Protein Name

nephronophthisis 3 (adolescent)

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000007584

InnateDB Gene

IDBG-639019 (NPHP3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0001822	kidney development
GO:0001947	heart looping
GO:0003283	atrial septum development
GO:0006629	lipid metabolic process
GO:0007163	establishment or maintenance of cell polarity
GO:0007368	determination of left/right symmetry
GO:0030198	extracellular matrix organization
GO:0030324	lung development
GO:0030814	regulation of cAMP metabolic process
GO:0035469	determination of pancreatic left/right asymmetry
GO:0045494	photoreceptor cell maintenance
GO:0048496	maintenance of organ identity
GO:0060027	convergent extension involved in gastrulation
GO:0060993	kidney morphogenesis
GO:0071908	determination of intestine left/right asymmetry
GO:0071909	determination of stomach left/right asymmetry
GO:0071910	determination of liver left/right asymmetry
GO:0072189	ureter development
GO:0090090	negative regulation of canonical Wnt signaling pathway

Cellular Component

GO:0005929	cilium
GO:0072372	primary cilium

Protein Structure and Domains

PDB ID

InterPro

IPR001440 Tetratricopeptide TPR1
IPR011716 Tetratricopeptide TPR-3
IPR013026 Tetratricopeptide repeat-containing domain
IPR019734 Tetratricopeptide repeat
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00515
PF07720
PF13174
PF13176
PF13181

PRINTS

PIRSF

SMART

SM00028

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite