Version 5.4
Bos taurus Protein: KCNN4
Summary
InnateDB Protein IDBP-691304.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNN4
Protein Name intermediate conductance calcium-activated potassium channel protein 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000006024
InnateDB Gene IDBG-639154 (KCNN4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005267 potassium channel activity
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0015269 calcium-activated potassium channel activity
GO:0016286 small conductance calcium-activated potassium channel activity
GO:0019903 protein phosphatase binding
GO:0022894 Intermediate conductance calcium-activated potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0006816 calcium ion transport
GO:0006884 cell volume homeostasis
GO:0030322 stabilization of membrane potential
GO:0045332 phospholipid translocation
GO:0046541 saliva secretion
GO:0050714 positive regulation of protein secretion
GO:0050862 positive regulation of T cell receptor signaling pathway
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID
InterPro IPR004178 Calmodulin-binding domain
IPR013099 Two pore domain potassium channel domain
IPR015449 Potassium channel, calcium-activated, SK
PFAM PF02888
PF07885
PF03530
PRINTS PR01451
PIRSF
SMART SM01053
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1BFX7
UniProt Splice Variant
Entrez Gene 534591
UniGene Bt.28543
RefSeq XP_005219369
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02047260 DAAA02047261
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca