Version 5.4
Bos taurus Protein: PROC
Summary
InnateDB Protein IDBP-691356.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PROC
Protein Name vitamin K-dependent protein C
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000005163
InnateDB Gene IDBG-639221 (PROC)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0007596 blood coagulation
GO:0030195 negative regulation of blood coagulation
GO:0043066 negative regulation of apoptotic process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000294 Gamma-carboxyglutamic acid-rich (GLA) domain
IPR000742 Epidermal growth factor-like domain
IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR001881 EGF-like calcium-binding domain
IPR009003 Trypsin-like cysteine/serine peptidase domain
IPR012224 Peptidase S1A, coagulation factor VII/IX/X/C/Z
PFAM PF00594
PF00008
PF00089
PF07645
PRINTS PR00001
PR00722
PIRSF PIRSF001143
SMART SM00069
SM00181
SM00020
SM00179
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 281428
UniGene
RefSeq NP_001159984
HUGO HGNC:9451
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca