InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.65130

Summary

InnateDB Protein

IDBP-691399.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.65130

Protein Name

steroid 17-alpha-hydroxylase/17,20 lyase

Synonyms

CYP17; CYPXVII; P450-C17; P450c17;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000019061

InnateDB Gene

IDBG-639257 (BT.65130)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004497	monooxygenase activity
GO:0004508	steroid 17-alpha-monooxygenase activity
GO:0005506	iron ion binding
GO:0016491	oxidoreductase activity
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037	heme binding
GO:0046872	metal ion binding

Biological Process

GO:0006704	glucocorticoid biosynthetic process
GO:0008202	steroid metabolic process
GO:0042446	hormone biosynthetic process
GO:0042448	progesterone metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0030424	axon
GO:0043025	neuronal cell body

Protein Structure and Domains

PDB ID

InterPro

IPR001128 Cytochrome P450
IPR002401 Cytochrome P450, E-class, group I
IPR002403 Cytochrome P450, E-class, group IV

PFAM

PF00067

PRINTS

PR00385
PR00463
PR00465

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q9TRV0

UniProt Splice Variant

Entrez Gene

785462

UniGene

Bt.89153

RefSeq

NP_776729

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02059027

GenPept