Version 5.4
Bos taurus Protein: APOC2
Summary
InnateDB Protein IDBP-691455.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APOC2
Protein Name Apolipoprotein C-IIApolipoprotein C-II short form
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000027393
InnateDB Gene IDBG-639315 (APOC2)
Protein Structure
UniProt Annotation
Function Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly.
Subcellular Localization Secreted.
Disease Associations
Tissue Specificity Secreted in plasma.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008047 enzyme activator activity
GO:0060230 lipoprotein lipase activator activity
Biological Process
GO:0006629 lipid metabolic process
GO:0006810 transport
GO:0006869 lipid transport
GO:0010898 positive regulation of triglyceride catabolic process
GO:0016042 lipid catabolic process
GO:0045723 positive regulation of fatty acid biosynthetic process
GO:0051006 positive regulation of lipoprotein lipase activity
Cellular Component
GO:0005576 extracellular region
GO:0034361 very-low-density lipoprotein particle
GO:0042627 chylomicron
Protein Structure and Domains
PDB ID
InterPro IPR008019 Apolipoprotein C-II
PFAM PF05355
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P19034
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 618039
UniGene Bt.52373
RefSeq NP_001095850
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF007114 BC146135
GenPept AAB63893 AAI46136

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca