Bos taurus Protein: ORC1 | |||||||||||||
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Summary | |||||||||||||
InnateDB Protein | IDBP-691516.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | ORC1 | ||||||||||||
Protein Name | origin recognition complex subunit 1 | ||||||||||||
Synonyms | ORC1L; | ||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Protein | ENSBTAP00000048350 | ||||||||||||
InnateDB Gene | IDBG-639359 (ORC1) | ||||||||||||
Protein Structure | |||||||||||||
UniProt Annotation | |||||||||||||
Function | Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication (By similarity). {ECO:0000250}. | ||||||||||||
Subcellular Localization | Nucleus {ECO:0000250}. | ||||||||||||
Disease Associations | |||||||||||||
Tissue Specificity | |||||||||||||
Comments | |||||||||||||
Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||||
PDB ID | |||||||||||||
InterPro |
IPR001025
Bromo adjacent homology (BAH) domain IPR003593 AAA+ ATPase domain IPR003959 ATPase, AAA-type, core IPR015163 CDC6, C-terminal domain IPR018647 Domain of unknown function DUF2075 IPR027417 P-loop containing nucleoside triphosphate hydrolase |
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PFAM |
PF01426
PF00004 PF07724 PF13304 PF09079 PF09848 |
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PRINTS | |||||||||||||
PIRSF | |||||||||||||
SMART |
SM00439
SM00382 SM01074 |
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TIGRFAMs | |||||||||||||
Post-translational Modifications | |||||||||||||
Modification | |||||||||||||
Cross-References | |||||||||||||
SwissProt | Q58DC8 | ||||||||||||
PhosphoSite | PhosphoSite- | ||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | 513523 | ||||||||||||
UniGene | Bt.2111 | ||||||||||||
RefSeq | NP_001014918 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | BC133326 BT021669 | ||||||||||||
GenPept | AAI33327 AAX46516 | ||||||||||||