Version 5.4
Bos taurus Protein: CKM
Summary
InnateDB Protein IDBP-691602.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CKM
Protein Name Creatine kinase M-type
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000018492
InnateDB Gene IDBG-639439 (CKM)
Protein Structure
UniProt Annotation
Function Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0004111 creatine kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0016310 phosphorylation
GO:0046314 phosphocreatine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR022413 ATP:guanido phosphotransferase, N-terminal
IPR022414 ATP:guanido phosphotransferase, catalytic domain
PFAM PF02807
PF00217
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9XSC6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 286822
UniGene Bt.3651
RefSeq NP_777198
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF120106 BC102907 BT020785 BT021173
GenPept AAD30974 AAI02908 AAX08802 AAX31355

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca