Version 5.4
Bos taurus Gene: CKM
Summary
InnateDB Gene IDBG-639439.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CKM
Gene Name Creatine kinase M-type
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013921
Encoded Proteins
IDBP-691602
Creatine kinase M-type
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104879:
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:53383534-53392948
Strand Reverse strand
Band
Transcripts
ENSBTAT00000018492 ENSBTAP00000018492
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0004111 creatine kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0016310 phosphorylation
GO:0046314 phosphocreatine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000104879
View Gene Order
ENSMUSG00000030399
View Gene Order
Pathways
NETPATH
REACTOME
REACT_226362
Metabolism of amino acids and derivatives pathway
REACT_207339
Creatine metabolism pathway
REACT_219139
Metabolism pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_813
Creatine metabolism pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
REACT_239426
Creatine metabolism pathway
REACT_188937
Metabolism pathway
REACT_232845
Metabolism of amino acids and derivatives pathway
KEGG
hsa00330
Arginine and proline metabolism pathway
mmu00330
Arginine and proline metabolism pathway
INOH
INOH website
Arginine Proline metabolism pathway
PID NCI
rb_1pathway
Regulation of retinoblastoma protein
Cross-References
SwissProt Q9XSC6
TrEMBL
UniProt Splice Variant
Entrez Gene 286822
UniGene Bt.3651
RefSeq NM_174773
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AF120106 BC102907 BT020785 BT021173
GenPept AAD30974 AAI02908 AAX08802 AAX31355
RNA Seq Atlas 286822

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca