Version 5.4
Bos taurus Protein: CBS
Summary
InnateDB Protein IDBP-691770.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CBS
Protein Name cystathionine beta-synthase
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000000184
InnateDB Gene IDBG-639589 (CBS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004122 cystathionine beta-synthase activity
GO:0030554 adenyl nucleotide binding
Biological Process
GO:0001958 endochondral ossification
GO:0001974 blood vessel remodeling
GO:0006535 cysteine biosynthetic process from serine
GO:0006801 superoxide metabolic process
GO:0019343 cysteine biosynthetic process via cystathionine
GO:0019344 cysteine biosynthetic process
GO:0021587 cerebellum morphogenesis
GO:0030823 regulation of cGMP metabolic process
GO:0043506 regulation of JUN kinase activity
GO:0050667 homocysteine metabolic process
GO:0050880 regulation of blood vessel size
GO:0051593 response to folic acid
GO:0060135 maternal process involved in female pregnancy
GO:0060351 cartilage development involved in endochondral bone morphogenesis
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000644 CBS domain
IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme
IPR005857 Cystathionine beta-synthase
PFAM PF00571
PF00291
PRINTS
PIRSF
SMART SM00116
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MEW4
UniProt Splice Variant
Entrez Gene 514525
UniGene Bt.15688
RefSeq NP_001095470
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02003311 DAAA02003312
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca