InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: PSPH

Summary

InnateDB Protein

IDBP-691879.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PSPH

Protein Name

Phosphoserine phosphatase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000017392

InnateDB Gene

IDBG-639694 (PSPH)

Protein Structure

UniProt Annotation

Function

Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004647	phosphoserine phosphatase activity
GO:0005509	calcium ion binding
GO:0008253	5'-nucleotidase activity
GO:0016787	hydrolase activity
GO:0016791	phosphatase activity
GO:0042803	protein homodimerization activity
GO:0046872	metal ion binding

Biological Process

GO:0006563	L-serine metabolic process
GO:0006564	L-serine biosynthetic process
GO:0008152	metabolic process
GO:0008652	cellular amino acid biosynthetic process
GO:0016311	dephosphorylation

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR004469 Phosphoserine phosphatase SerB
IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like
IPR006434 Pyrimidine 5\'-nucleotidase, eukaryotic
IPR016965 Phosphatase PHOSPHO-type
IPR023214 HAD-like domain

PFAM

PF05822
PF06888
PF00702
PF08282
PF13419

PRINTS

PIRSF

PIRSF031051

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q2KHU0