InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PSPH

Summary

InnateDB Gene

IDBG-639694.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PSPH

Gene Name

Phosphoserine phosphatase

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000013081

Encoded Proteins

IDBP-691879

Phosphoserine phosphatase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146733:
The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 25:27955045-27977149

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000017392

ENSBTAP00000017392

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0004647	phosphoserine phosphatase activity
GO:0005509	calcium ion binding
GO:0008253	5'-nucleotidase activity
GO:0016787	hydrolase activity
GO:0016791	phosphatase activity
GO:0042803	protein homodimerization activity
GO:0046872	metal ion binding

Biological Process

GO:0006563	L-serine metabolic process
GO:0006564	L-serine biosynthetic process
GO:0008152	metabolic process
GO:0008652	cellular amino acid biosynthetic process
GO:0016311	dephosphorylation