InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: BT.56893

Summary

InnateDB Protein

IDBP-691950.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.56893

Protein Name

activation-induced cytidine deaminase

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000025096

InnateDB Gene

IDBG-639763 (BT.56893)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 66 interaction(s) predicted by orthology.

Predicted by orthology
Total	66 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004126	cytidine deaminase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016787	hydrolase activity
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines

Biological Process

GO:0009972	cytidine deamination
GO:0016445	somatic diversification of immunoglobulins
GO:0016446	somatic hypermutation of immunoglobulin genes
GO:0045190	isotype switching
GO:0071222	cellular response to lipopolysaccharide
GO:0080111	DNA demethylation
GO:0090310	negative regulation of methylation-dependent chromatin silencing

Cellular Component

GO:0000178	exosome (RNase complex)
GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR007904 APOBEC-like, C-terminal
IPR013158 APOBEC-like, N-terminal
IPR016193 Cytidine deaminase-like

PFAM

PF05240
PF08210

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F1MV53

UniProt Splice Variant

Entrez Gene

539888

UniGene

Bt.56893

RefSeq

NP_001033771

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02014394

GenPept