Version 5.4
Bos taurus Protein: CDS2
Summary
InnateDB Protein IDBP-692025.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDS2
Protein Name Phosphatidate cytidylyltransferase 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000007970
InnateDB Gene IDBG-639830 (CDS2)
Protein Structure
UniProt Annotation
Function Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. {ECO:0000250}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}; Matrix side {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004605 phosphatidate cytidylyltransferase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0008654 phospholipid biosynthetic process
GO:0016024 CDP-diacylglycerol biosynthetic process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005783 endoplasmic reticulum
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000374 Phosphatidate cytidylyltransferase
IPR016720 Phosphatidate cytidylyltransferase, eukaryota
PFAM PF01148
PRINTS
PIRSF PIRSF018269
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A0JNC1
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 614834
UniGene Bt.2342
RefSeq NP_001071514
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126607
GenPept AAI26608

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca