Bos taurus Protein: LIG1
Summary
InnateDB Protein IDBP-692371.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LIG1
Protein Name DNA ligase 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000031866
InnateDB Gene IDBG-640139 (LIG1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003677 DNA binding
GO:0003909 DNA ligase activity
GO:0003910 DNA ligase (ATP) activity
GO:0005524 ATP binding
GO:0016874 ligase activity
Biological Process
GO:0006260 DNA replication
GO:0006266 DNA ligation
GO:0006273 lagging strand elongation
GO:0006281 DNA repair
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006310 DNA recombination
GO:0006974 cellular response to DNA damage stimulus
GO:0042542 response to hydrogen peroxide
GO:0051103 DNA ligation involved in DNA repair
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005739 mitochondrion
GO:0005794 Golgi apparatus
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR000977 DNA ligase, ATP-dependent
IPR012308 DNA ligase, ATP-dependent, N-terminal
IPR012309 DNA ligase, ATP-dependent, C-terminal
IPR012310 DNA ligase, ATP-dependent, central
IPR012340 Nucleic acid-binding, OB-fold
PFAM PF04675
PF04679
PF01068
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A4IFC8
UniProt Splice Variant
Entrez Gene 100124507
UniGene Bt.12876
RefSeq NP_001096018
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134518 DAAA02047435
GenPept AAI34519