Version 5.4
Bos taurus Protein: PLK3
Summary
InnateDB Protein IDBP-692461.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLK3
Protein Name serine/threonine-protein kinase PLK3
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000008055
InnateDB Gene IDBG-640223 (PLK3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0002039 p53 binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000084 mitotic S phase
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0000302 response to reactive oxygen species
GO:0006468 protein phosphorylation
GO:0006970 response to osmotic stress
GO:0006974 cellular response to DNA damage stimulus
GO:0009314 response to radiation
GO:0016310 phosphorylation
GO:0031122 cytoplasmic microtubule organization
GO:0043066 negative regulation of apoptotic process
GO:0051302 regulation of cell division
GO:0090166 Golgi disassembly
GO:0090316 positive regulation of intracellular protein transport
GO:2000777 positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005795 Golgi stack
GO:0005813 centrosome
Protein Structure and Domains
PDB ID
InterPro IPR000719 Protein kinase domain
IPR000959 POLO box duplicated domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR020635 Tyrosine-protein kinase, catalytic domain
PFAM PF00069
PF00659
PF07714
PRINTS PR00109
PIRSF
SMART SM00220
SM00219
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q0VCE7
UniProt Splice Variant
Entrez Gene 504282
UniGene Bt.21013
RefSeq NP_001068621
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120205 DAAA02009018
GenPept AAI20206

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca