InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PLK3

Summary

InnateDB Gene

IDBG-640223.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PLK3

Gene Name

serine/threonine-protein kinase PLK3

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000006125

Encoded Proteins

IDBP-692461

serine/threonine-protein kinase PLK3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173846:
Cytokine-inducible kinase is a putative serine/threonine kinase. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis. [provided by RefSeq, Jul 2008]
Cytokine-inducible kinase is a putative serine/threonine kinase. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:101792010-101796880

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000008055

ENSBTAP00000008055

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0002039	p53 binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0000082	G1/S transition of mitotic cell cycle
GO:0000084	mitotic S phase
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0000302	response to reactive oxygen species
GO:0006468	protein phosphorylation
GO:0006970	response to osmotic stress
GO:0006974	cellular response to DNA damage stimulus
GO:0009314	response to radiation
GO:0016310	phosphorylation
GO:0031122	cytoplasmic microtubule organization
GO:0043066	negative regulation of apoptotic process
GO:0051302	regulation of cell division
GO:0090166	Golgi disassembly
GO:0090316	positive regulation of intracellular protein transport
GO:2000777	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia