InnateDB Protein
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IDBP-692600.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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DPH2
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Protein Name
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diphthamide biosynthesis protein 2
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Synonyms
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Species
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Bos taurus
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Ensembl Protein
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ENSBTAP00000025143
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InnateDB Gene
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IDBG-640346 (DPH2)
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Protein Structure
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Function |
Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2). {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
GO:0017183
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peptidyl-diphthamide biosynthetic process from peptidyl-histidine
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Cellular Component |
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PDB ID |
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InterPro |
IPR002728
Diphthamide synthesis, DPH1/DPH2
IPR010014
Diphthamide synthesis DHP2, eukaryotic
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PFAM |
PF01866
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q08DM2
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
768224
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UniGene |
Bt.15775
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RefSeq |
NP_001071567
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HUGO |
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC123671
BT030476
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GenPept |
AAI23672
ABQ12916
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