Bos taurus Protein: DPH2
Summary
InnateDB Protein IDBP-692600.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DPH2
Protein Name diphthamide biosynthesis protein 2
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000025143
InnateDB Gene IDBG-640346 (DPH2)
Protein Structure
UniProt Annotation
Function Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0017183 peptidyl-diphthamide biosynthetic process from peptidyl-histidine
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR002728 Diphthamide synthesis, DPH1/DPH2
IPR010014 Diphthamide synthesis DHP2, eukaryotic
PFAM PF01866
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q08DM2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 768224
UniGene Bt.15775
RefSeq NP_001071567
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC123671 BT030476
GenPept AAI23672 ABQ12916