InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: FTL

Summary

InnateDB Protein

IDBP-692603.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FTL

Protein Name

Ferritin light chain

Synonyms

Species

Bos taurus

Ensembl Protein

ENSBTAP00000009965

InnateDB Gene

IDBG-640350 (FTL)

Protein Structure

UniProt Annotation

Function

Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005506	iron ion binding
GO:0008199	ferric iron binding
GO:0046872	metal ion binding

Biological Process

GO:0006826	iron ion transport
GO:0006879	cellular iron ion homeostasis

Cellular Component

GO:0008043

intracellular ferritin complex

Protein Structure and Domains

PDB ID

InterPro

IPR008331 Ferritin/DPS protein domain
IPR009040 Ferritin- like diiron domain
IPR009078 Ferritin-like superfamily

PFAM

PF00210

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O46415

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

788801

UniGene

Bt.87069

RefSeq

NP_777217

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AB003094 AY528246 BC103021

GenPept

AAI03022 AAS20594 BAA24819