Version 5.4
| Bos taurus Gene: FTL | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-640350.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | FTL | ||||||||
| Gene Name | Ferritin light chain | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000013343 | ||||||||
| Encoded Proteins |
Ferritin light chain
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000087086:
This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 18:55992910-55994741 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Iron uptake and transport pathway
Transmembrane transport of small molecules pathway
Scavenging by Class A Receptors pathway
Binding and Uptake of Ligands by Scavenger Receptors pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Iron uptake and transport pathway
Golgi Associated Vesicle Biogenesis pathway
Clathrin derived vesicle budding pathway
Transmembrane transport of small molecules pathway
trans-Golgi Network Vesicle Budding pathway
Binding and Uptake of Ligands by Scavenger Receptors pathway
Scavenging by Class A Receptors pathway
Membrane Trafficking pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | O46415 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 788801 | ||||||||
| UniGene | Bt.109450 Bt.87069 | ||||||||
| RefSeq | NM_174792 XM_003583919 XM_003585206 XM_003587735 XM_005198719 XM_005208301 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AB003094 AY528246 BC103021 | ||||||||
| GenPept | AAI03022 AAS20594 BAA24819 | ||||||||
| RNA Seq Atlas | 100850238 101904953 286861 788801 | ||||||||