Version 5.4
Bos taurus Protein: PLEKHA1
Summary
InnateDB Protein IDBP-692849.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLEKHA1
Protein Name pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000006081
InnateDB Gene IDBG-640567 (PLEKHA1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0030165 PDZ domain binding
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
Biological Process
GO:0001553 luteinization
GO:0007283 spermatogenesis
GO:0008209 androgen metabolic process
GO:0008210 estrogen metabolic process
GO:0008585 female gonad development
GO:0009791 post-embryonic development
GO:0014065 phosphatidylinositol 3-kinase signaling
GO:0031529 ruffle organization
GO:0033327 Leydig cell differentiation
GO:0035264 multicellular organism growth
GO:0045184 establishment of protein localization
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048705 skeletal system morphogenesis
GO:0050853 B cell receptor signaling pathway
GO:0051898 negative regulation of protein kinase B signaling
GO:0060021 palate development
GO:0060325 face morphogenesis
GO:0070301 cellular response to hydrogen peroxide
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0032587 ruffle membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001849 Pleckstrin homology domain
PFAM PF00169
PRINTS
PIRSF
SMART SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q0IIA5
UniProt Splice Variant
Entrez Gene 513040
UniGene Bt.101365
RefSeq NP_001069061
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC122736 DAAA02059451 DAAA02059452
GenPept AAI22737

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca