InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Protein: DOCK1

Summary

InnateDB Protein

IDBP-693304.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DOCK1

Protein Name

dedicator of cytokinesis 1

Synonyms

DOCK180;

Species

Bos taurus

Ensembl Protein

ENSBTAP00000032659

InnateDB Gene

IDBG-640952 (DOCK1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.

Predicted by orthology
Total	20 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005085	guanyl-nucleotide exchange factor activity
GO:0005488	binding
GO:0005515	protein binding
GO:0009055	electron carrier activity
GO:0020037	heme binding

Biological Process

GO:0002244	hematopoietic progenitor cell differentiation
GO:0007264	small GTPase mediated signal transduction
GO:0016477	cell migration
GO:0043547	positive regulation of GTPase activity

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR001452 SH3 domain
IPR009056 Cytochrome c-like domain
IPR010703 Dedicator of cytokinesis C-terminal
IPR011511 Variant SH3 domain
IPR016024 Armadillo-type fold

PFAM

PF00018
PF14604
PF13442
PF06920
PF07653

PRINTS

PR00452

PIRSF

SMART

SM00326

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt