Version 5.4
Bos taurus Protein: EDN3
Summary
InnateDB Protein IDBP-693455.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EDN3
Protein Name endothelin 3
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000052537
InnateDB Gene IDBG-641126 (EDN3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
GO:0001755 neural crest cell migration
GO:0002690 positive regulation of leukocyte chemotaxis
GO:0003100 regulation of systemic arterial blood pressure by endothelin
GO:0007166 cell surface receptor signaling pathway
GO:0008284 positive regulation of cell proliferation
GO:0010460 positive regulation of heart rate
GO:0014826 vein smooth muscle contraction
GO:0019229 regulation of vasoconstriction
GO:0030072 peptide hormone secretion
GO:0030182 neuron differentiation
GO:0030318 melanocyte differentiation
GO:0030334 regulation of cell migration
GO:0030593 neutrophil chemotaxis
GO:0042310 vasoconstriction
GO:0043406 positive regulation of MAP kinase activity
GO:0045840 positive regulation of mitosis
GO:0046887 positive regulation of hormone secretion
GO:0048016 inositol phosphate-mediated signaling
GO:0048070 regulation of developmental pigmentation
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR001928 Endothelin-like toxin
IPR020475 Bibrotoxin/Sarafotoxin-D
PFAM PF00322
PRINTS PR00365
PIRSF
SMART SM00272
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E1B9R6
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:3178
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02036308 DAAA02036309 DAAA02036310
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca