Version 5.4
Bos taurus Protein: CARD11
Summary
InnateDB Protein IDBP-693533.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CARD11
Protein Name caspase recruitment domain-containing protein 11
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000036945
InnateDB Gene IDBG-641196 (CARD11)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0050700 CARD domain binding
Biological Process
GO:0001819 positive regulation of cytokine production
GO:0007165 signal transduction
GO:0030890 positive regulation of B cell proliferation
GO:0031295 T cell costimulation
GO:0042102 positive regulation of T cell proliferation
GO:0042981 regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045061 thymic T cell selection
GO:0045086 positive regulation of interleukin-2 biosynthetic process
GO:0045577 regulation of B cell differentiation
GO:0045580 regulation of T cell differentiation
GO:0050776 regulation of immune response
GO:0050870 positive regulation of T cell activation
GO:0051092 positive regulation of NF-kappaB transcription factor activity
Cellular Component
GO:0001772 immunological synapse
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0042101 T cell receptor complex
GO:0045121 membrane raft
Protein Structure and Domains
PDB ID
InterPro IPR001315 CARD domain
IPR001478 PDZ domain
IPR011029 Death-like domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00619
PF00595
PF13180
PRINTS
PIRSF
SMART SM00114
SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A8E646
UniProt Splice Variant
Entrez Gene 515377
UniGene Bt.43438
RefSeq NP_001103266
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC153839 DAAA02058388 DAAA02058389 DAAA02058390 DAAA02058391
GenPept AAI53840

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca