Bos taurus Gene: CARD11 | |||||||||||||||||||||||||||||
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Summary | |||||||||||||||||||||||||||||
InnateDB Gene | IDBG-641196.3 | ||||||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||||||
Gene Symbol | CARD11 | ||||||||||||||||||||||||||||
Gene Name | caspase recruitment domain-containing protein 11 | ||||||||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||||||||||
Ensembl Gene | ENSBTAG00000014698 | ||||||||||||||||||||||||||||
Encoded Proteins |
caspase recruitment domain-containing protein 11
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Protein Structure | |||||||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198286:
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||||||
Genomic Location | Chromosome 25:40960556-41068746 | ||||||||||||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||||||||||||
Band | |||||||||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||||||||
NETPATH |
TCR pathway
BCR pathway
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REACTOME |
Downstream TCR signaling pathway
Activation of NF-kappaB in B cells pathway
FCERI mediated NF-kB activation pathway
TCR signaling pathway
Innate Immune System pathway
Fc epsilon receptor (FCERI) signaling pathway
Adaptive Immune System pathway
Immune System pathway
Signaling by the B Cell Receptor (BCR) pathway
Downstream signaling events of B Cell Receptor (BCR) pathway
Innate Immune System pathway
Signaling by the B Cell Receptor (BCR) pathway
Downstream TCR signaling pathway
FCERI mediated NF-kB activation pathway
Immune System pathway
Activation of NF-kappaB in B cells pathway
Fc epsilon receptor (FCERI) signaling pathway
Adaptive Immune System pathway
TCR signaling pathway
Downstream signaling events of B Cell Receptor (BCR) pathway
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KEGG |
B cell receptor signaling pathway pathway
T cell receptor signaling pathway pathway
T cell receptor signaling pathway pathway
B cell receptor signaling pathway pathway
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INOH |
CD4 T cell receptor signaling pathway
B cell receptor signaling pathway
CD4 T cell receptor signaling pathway
B cell receptor signaling pathway
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PID NCI |
TCR signaling in naïve CD8+ T cells
TCR signaling in naïve CD4+ T cells
BCR signaling pathway
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Cross-References | |||||||||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||||||||
TrEMBL | A8E646 | ||||||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||||||
Entrez Gene | 515377 | ||||||||||||||||||||||||||||
UniGene | Bt.43438 | ||||||||||||||||||||||||||||
RefSeq | NM_001109796 XM_005225104 XM_005225105 XM_005225106 XM_005225107 XM_005225108 XM_005225109 | ||||||||||||||||||||||||||||
HUGO | |||||||||||||||||||||||||||||
OMIM | |||||||||||||||||||||||||||||
CCDS | |||||||||||||||||||||||||||||
HPRD | |||||||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||||||
EMBL | BC153839 DAAA02058388 DAAA02058389 DAAA02058390 DAAA02058391 | ||||||||||||||||||||||||||||
GenPept | AAI53840 | ||||||||||||||||||||||||||||
RNA Seq Atlas | 515377 | ||||||||||||||||||||||||||||