Version 5.4
Bos taurus Protein: BNIP3
Summary
InnateDB Protein IDBP-693540.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BNIP3
Protein Name BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000023684
InnateDB Gene IDBG-641206 (BNIP3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046982 protein heterodimerization activity
GO:0051020 GTPase binding
Biological Process
GO:0006915 apoptotic process
GO:0008626 granzyme-mediated apoptotic signaling pathway
GO:0010637 negative regulation of mitochondrial fusion
GO:0035694 mitochondrial protein catabolic process
GO:0043065 positive regulation of apoptotic process
GO:0043068 positive regulation of programmed cell death
GO:0043243 positive regulation of protein complex disassembly
GO:0043653 mitochondrial fragmentation involved in apoptotic process
GO:0045837 negative regulation of membrane potential
GO:0046902 regulation of mitochondrial membrane permeability
GO:0050873 brown fat cell differentiation
GO:0051607 defense response to virus
GO:0071260 cellular response to mechanical stimulus
GO:0071279 cellular response to cobalt ion
GO:0071456 cellular response to hypoxia
GO:0072593 reactive oxygen species metabolic process
GO:0090141 positive regulation of mitochondrial fission
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0097193 intrinsic apoptotic signaling pathway
GO:0097345 mitochondrial outer membrane permeabilization
GO:1990144 intrinsic apoptotic signaling pathway in response to hypoxia
Cellular Component
GO:0005635 nuclear envelope
GO:0005739 mitochondrion
GO:0005740 mitochondrial envelope
GO:0005741 mitochondrial outer membrane
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane
GO:0031307 integral component of mitochondrial outer membrane
GO:0031966 mitochondrial membrane
Protein Structure and Domains
PDB ID
InterPro IPR010548 BNIP3
PFAM PF06553
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F1MY27
UniProt Splice Variant
Entrez Gene 615342
UniGene
RefSeq NP_001069834
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02059703
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca